Opus Genetics posts OPGx-BEST1 Phase 1/2 low-dose cohort presentation update

Reuters2026/09/09 11:34

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Opus Genetics published 3-month Phase 1/2 results for OPGx-BEST1 gene therapy in low-dose Cohort 1 for BEST1-related retinal disease.
Safety profile: no serious adverse events, no dose-limiting toxicities, no intraocular inflammation in 5 treated participants.
Early efficacy signals: 75% of evaluable participants met an FDA-aligned microperimetry threshold of at least 3 dB improvement in 5 loci.
Manufacturing timeline: Phase 3 and commercial supply targeted for early 2027; pivotal trial dosing planned in 2027.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Opus Genetics Inc. published the original content used to generate this news brief on September 09, 2026, and is solely responsible for the information contained therein.

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Opus Genetics posts OPGx-BEST1 Phase 1/2 low-dose cohort presentation update

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